Some actives boost each other’s effects, while others can cause irritation or cancel each other out when layered incorrectly. Here are a few gold-standard synergies:
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* Retinoids + Peptides + Growth Factors
¹
→ Retinoids accelerate cell turnover, peptides strengthen skin and support collagen, and growth factors enhance repair and regeneration—working together for firmer, healthier skin.
- * Antioxidants + SPF → Vitamin C neutralizes free radicals, and SPF prevents them—your best daytime defense.
- * Exfoliants + Hydrators → Acids remove dead skin so humectants like hyaluronic acid can deeply hydrate.
Before we get into targeted routines, here’s how to apply products (from thinnest to thickest) so that your actives absorb properly:
1. Cleanse → Removes dirt, oil, and buildup so actives penetrate efficiently
2. Tone → Preps the skin and balances pH
3. Serums → Deliver the most concentrated dose of actives
4. Moisturizer → Seals everything in, preventing water loss
5. SPF (AM only) → Shields skin from UV damage and protects active ingredients
How to layer actives based on your skincare goals
For Brightening & Hyperpigmentation
Get these actives: retinol, glycolic acid, niacinamide
Epi.Logic Routine:
- * Morning: Clean Reveal → Even Balance → The Total Package → SPF
- * Night: True Calm → Even Balance → Double Feature → The Total Package
For Collagen Support & Firmness
Get these actives: Retinol, peptides, growth factors
Epi.Logic Routine:
- * Morning: True Calm → Master Plan → The Total Package → SPF
- * Night: Clean Reveal → Double Feature → Eye Contact → The Total Package
For Dullness & Barrier Support
Get these actives: Hyaluronic acid, glycolic acid, growth factors
Epi.Logic Routine:
- * Morning: Clean Reveal → Even Balance → The Total Package → SPF
- * Night: True Calm → Master Plan → Double Feature → The Total Package
Smart skincare isn’t about piling on every active—it’s about using the right ones, the right way. Thoughtful formulation, strategic layering, and consistency are what truly drive results. At epi.logic, every product is designed with this balance in mind—so your skin gets exactly what it needs, nothing it doesn’t.
¹ Gorouhi F, Maibach HI. Role of topical peptides in preventing or treating aged skin. Int J Cosmet Sci. 2009 Oct;31(5):327-45. doi: 10.1111/j.1468-2494.2009.00490.x. Epub 2009 Jun 30. PMID: 19570099.
